Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | F13A1 | P00488 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645436 | 0.88 | KDM4E (0.54) | ALDH1A1HTTTSHRRAB9AMAPT | |
| SCHEMBL11666892 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL11645434 | 0.86 | XIAP (0.58) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL11671917 | 0.83 | ALDH1A1 (0.55) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL11748157 | 0.82 | MTNR1B (0.68) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL11642407 | 0.82 | MITF (0.57) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL11641273 | 0.82 | POLB (0.56) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL7400630 | 0.80 | MEN1 (0.52) | ALDH1A1MITFPOLBMAPK1HTT | |
| SCHEMBL10603318 | 0.80 | KDM4E (0.47) | ALDH1A1POLBMAPK1TSHRRAB9A | |
| SCHEMBL11642716 | 0.80 | MTNR1B (0.64) | ALDH1A1TSHRRAB9AHPGDMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |