SCHEMBL11646263

SCHEMBL11646263

CCCCCCCCc1cc(C)c(C)c(C)c1CCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.44
ALOX5 P09917 7/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LIPG Q9Y5X9 1/20 0.39
CYP19A1 P11511 1/20 0.39
PTGS2 P35354 5/20 0.38
CCR5 P51681 2/20 0.37
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29477173 0.86 TYR (0.46) TYRALOX5MEN1TP53CYP3A4
Ammonia Solution, Strong SCHEMBL30483961 0.84 TYR (0.44) TYRALOX5MEN1TP53CYP3A4
Hydrogen Sulfide SCHEMBL28200014 0.84 TYR (0.44) TYRALOX5MEN1TP53CYP3A4
SCHEMBL20816041 0.81 ALOX5 (0.48) TYRALOX5MEN1TP53CYP3A4
SCHEMBL31522306 0.79 SKP2 (0.41) TYRALOX5MEN1TP53CYP3A4
SCHEMBL250347 0.79 ALOX5 (0.47) TYRALOX5MEN1TP53CYP3A4
SCHEMBL29037315 0.79 ALOX5 (0.47) TYRALOX5MEN1TP53CYP3A4
SCHEMBL30640325 0.78 CYP19A1 (0.53) TYRALOX5MEN1TP53CYP3A4
SCHEMBL28496511 0.78 THRB (0.38) TYRALOX5CYP3A4CYP19A1PTGS2
SCHEMBL24784332 0.78 TLR8 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103080114-B Benzene azole dithiophene organic semiconductor material and preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2015-05-06 CN disclosed
US-4085155-A FROM ACETONE AND 1-ALKANOLS, CATALYTIC CONTINENTAL OIL COMPANY (US) 1978-04-18 US disclosed