SCHEMBL24784332

SCHEMBL24784332

CCc1c(CCCCCCCCCCN)cc(C)c(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 13/20 0.34
MPO P05164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11646263 0.78 TYR (0.44)
SCHEMBL28101513 0.77 KDM4E (0.33)
SCHEMBL4085470 0.75 NOS3 (0.34)
SCHEMBL19908564 0.73 HRH1 (0.41) TLR8
SCHEMBL17277547 0.68 MPO (0.40) TLR8MPO
SCHEMBL29477173 0.68 TYR (0.46)
SCHEMBL20019858 0.67 MAOA (0.46) TLR8
SCHEMBL17277546 0.67 MPO (0.39) TLR8MPO
SCHEMBL21130811 0.67 DNM1 (0.52) TLR8
Ammonia Solution, Strong SCHEMBL30483961 0.67 TYR (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022265178-A1 TRAP1 INHIBITOR AND USE THEREOF 주식회사 스마틴바이오 2022-12-22 WO disclosed