Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366821 | 0.87 | AKR1C3 (0.67) | MAPTSMN1; SMN2GAATP53THRB | |
| SCHEMBL23093355 | 0.86 | ALDH1A1 (0.64) | MAPTSMN1; SMN2GAATP53THRB | |
| SCHEMBL21802493 | 0.86 | CYP19A1 (0.69) | MAPTSMN1; SMN2GAATP53THRB | |
| SCHEMBL8275670 | 0.83 | HDAC3 (0.79) | MAPTSMN1; SMN2GAATP53THRB | |
| SCHEMBL27181037 | 0.82 | MEN1 (0.66) | MAPTSMN1; SMN2GAATP53THRB | |
| SCHEMBL30926962 | 0.82 | MEN1 (0.66) | MAPTSMN1; SMN2GAATP53THRB | |
| SCHEMBL28262522 | 0.82 | MAPT (0.74) | MAPTSMN1; SMN2GAATP53THRB | |
| SCHEMBL23093556 | 0.81 | ALDH1A1 (0.62) | MAPTSMN1; SMN2GAATP53THRB | |
| SCHEMBL7449594 | 0.81 | MEN1 (0.84) | MAPTSMN1; SMN2THRBHDAC2HDAC8 | |
| SCHEMBL7444940 | 0.81 | MEN1 (0.65) | MAPTSMN1; SMN2TP53THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |