Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | IDH1 | O75874 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | TCF4 | P15884 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449594 | 0.87 | MEN1 (0.84) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL7449794 | 0.86 | MEN1 (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL27181037 | 0.86 | MEN1 (0.66) | MEN1KMT2AIDH1RAB9AMAPT | |
| SCHEMBL30926962 | 0.86 | MEN1 (0.66) | MEN1KMT2AIDH1RAB9AMAPT | |
| SCHEMBL27180042 | 0.86 | MEN1 (0.66) | MEN1KMT2AIDH1RAB9AMAPT | |
| SCHEMBL30926541 | 0.86 | MEN1 (0.66) | MEN1KMT2AIDH1RAB9AMAPT | |
| SCHEMBL30926720 | 0.85 | MEN1 (0.67) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL27181006 | 0.85 | MEN1 (0.67) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL27179830 | 0.85 | MEN1 (0.69) | MEN1KMT2AIDH1MAPTLMNA | |
| SCHEMBL7449268 | 0.84 | MEN1 (0.68) | MEN1KMT2ARAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |