Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136856 | 0.80 | TP53 (0.53) | L3MBTL1TP53ALDH1A1PKMKDM4E | |
| SCHEMBL20560642 | 0.79 | ALDH1A1 (0.50) | L3MBTL1TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL20560634 | 0.76 | ALDH1A1 (0.54) | TP53ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL2312487 | 0.72 | MEN1 (0.48) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL28158074 | 0.72 | ALDH1A1 (0.49) | ALDH1A1PKMKDM4EHTTMEN1 | |
| SCHEMBL25695968 | 0.71 | HTR7 (0.50) | TP53ALDH1A1PKMKDM4EHTT | |
| SCHEMBL27331113 | 0.71 | TP53 (0.49) | TP53ALDH1A1PKMKDM4EHTT | |
| SCHEMBL11650607 | 0.70 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL12100862 | 0.70 | ALDH1A1 (0.69) | L3MBTL1TP53ALDH1A1PKMKDM4E | |
| SCHEMBL29596265 | 0.70 | ALDH1A1 (0.69) | L3MBTL1TP53ALDH1A1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110444-A | MODIFY THE STRENGTH OF BIOLOGICAL MEMBRANES | THE CALIFORNIA POLYTECHNIC STATE UNIVERSITY FOUNDATION (US) | 1978-08-29 | — | — | US | disclosed |