Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20629743 | 1.00 | ALDH1A1 (0.37) | ALDH1A1HSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL115092 | 0.83 | ALDH1A1 (0.34) | ALDH1A1HSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL139800 | 0.82 | DRD2 (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL116370 | 0.81 | CHRM2 (0.42) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL115203 | 0.81 | CHRM2 (0.42) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL374638 | 0.81 | CHRM2 (0.42) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL25086450 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL823030 | 0.80 | CHRM2 (0.41) | HSD17B10CHRM2CHRM1CHRM3HPGD | |
| SCHEMBL23394548 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CHRM2CHRM1CHRM3 | |
| SCHEMBL13216511 | 0.80 | CHRM2 (0.41) | HSD17B10CHRM2CHRM1CHRM3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | ALDH1A1 1678/4885HSD17B10 1844/4885CHRM2 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.