Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570124 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL11652485 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL11573154 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL11571260 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL11572479 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDGLA | |
| SCHEMBL11572662 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10GLAKMT2A | |
| SCHEMBL11570859 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL11574037 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL11573064 | 0.73 | ALDH1A1 (0.55) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL7628551 | 0.71 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099909-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1978-07-11 | — | — | US | disclosed |