Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 17/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 17/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598396 | 0.88 | L3MBTL1 (0.48) | HDAC1 | |
| SCHEMBL5598393 | 0.88 | L3MBTL1 (0.48) | HDAC1 | |
| SCHEMBL1165045 | 0.86 | CA1 (0.51) | HDAC3HDAC8HDAC2HDAC1HDAC6 | |
| SCHEMBL3674926 | 0.86 | CA1 (0.51) | HDAC3HDAC8HDAC2HDAC1HDAC6 | |
| SCHEMBL6987937 | 0.83 | CA12 (0.55) | — | |
| SCHEMBL30944751 | 0.83 | CA12 (0.55) | — | |
| SCHEMBL3180689 | 0.82 | L3MBTL1 (0.61) | HDAC1HDAC6HDAC10 | |
| SCHEMBL208544 | 0.81 | EPHX2 (0.57) | HDAC1 | |
| SCHEMBL19853209 | 0.80 | L3MBTL1 (0.51) | HDAC1HDAC6HDAC10 | |
| SCHEMBL30711975 | 0.78 | HDAC8 (0.69) | HDAC3HDAC8HDAC2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102898378-A | Phthalazinone derivatives and application thereof | JIANGSU SIMCERE PHARM CO LTD | 2013-01-30 | — | — | CN | disclosed |