SCHEMBL11650620

SCHEMBL11650620

Cc1ccccc1C(=O)N(C)c1cccc(OC(C)C)c1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 13/20 0.45
HSD17B1 P14061 12/20 0.45
POLB P06746 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21620320 0.85 HSD17B2 (0.46) HSD17B2HSD17B1POLB
SCHEMBL21652269 0.83 HSD17B2 (0.46) HSD17B2HSD17B1POLB
SCHEMBL21620308 0.80 HSD17B2 (0.65) HSD17B2HSD17B1POLB
SCHEMBL21620317 0.78 HSD17B2 (0.59) HSD17B2HSD17B1KMT2AMEN1
SCHEMBL6785538 0.78 RXRA (0.45) HSD17B2HSD17B1POLBKMT2AMEN1
SCHEMBL529870 0.77 POLB (0.66) POLBKMT2AMEN1
SCHEMBL14518798 0.77 RXRA (0.44) HSD17B2HSD17B1KMT2AMEN1
SCHEMBL11207620 0.76 RAB9A (0.55) HSD17B2HSD17B1KMT2AMEN1
SCHEMBL23309678 0.75 HSD17B2 (0.41) HSD17B2HSD17B1
SCHEMBL11405611 0.74 RXRA (0.42) HSD17B2HSD17B1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3395795-B1 MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) 2023-07-19 EP disclosed
EP-3822253-A1 METHOD FOR PREPARING PROPANEDINITRILE OXIME ETHER COMPOUND AND INTERMEDIATE COMPOUND Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) 2021-05-19 EP disclosed
US-4105693-A REACTING ALKYL 2-ALKYL BENZOATE WITH AN ANILINE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1978-08-08 US disclosed