Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 18/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 16/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650620 | 0.83 | HSD17B2 (0.45) | HSD17B2HSD17B1POLB | |
| SCHEMBL21620320 | 0.82 | HSD17B2 (0.46) | HSD17B2HSD17B1POLB | |
| SCHEMBL21652268 | 0.79 | HSD17B2 (0.54) | HSD17B2HSD17B1 | |
| SCHEMBL21652226 | 0.78 | HSD17B2 (0.53) | HSD17B2HSD17B1 | |
| SCHEMBL11570386 | 0.77 | CETP (0.42) | — | |
| SCHEMBL6785538 | 0.75 | RXRA (0.45) | HSD17B2HSD17B1POLB | |
| SCHEMBL21652267 | 0.74 | KCNK3 (0.56) | — | |
| SCHEMBL14518798 | 0.74 | RXRA (0.44) | HSD17B2HSD17B1 | |
| SCHEMBL11663164 | 0.74 | CETP (0.40) | — | |
| SCHEMBL21620308 | 0.74 | HSD17B2 (0.65) | HSD17B2HSD17B1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | HSD17B2 1351/4885HSD17B1 1084/4885POLB 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.