SCHEMBL11650656

SCHEMBL11650656

O=C1c2ccccc2C(=O)c2c(Nc3ccccc3[N+](=O)[O-])cccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.61
PTPRC P08575 1/20 0.61
MAPK1 P28482 6/20 0.54
MAPT P10636 5/20 0.54
TDP1 Q9NUW8 3/20 0.54
ALDH1A1 P00352 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
EGFR P00533 1/20 0.54
PABPC1 P11940 1/20 0.54
CASP7 P55210 1/20 0.54
CYP1A2 P05177 3/20 0.54
HIF1A Q16665 2/20 0.50
CYP3A4 P08684 2/20 0.50
GNG2 P59768 1/20 0.50
GNB1 P62873 1/20 0.50
TP53 P04637 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11622598 0.86 MAPT (0.61) S100A4PTPRCMAPK1MAPTTDP1
SCHEMBL11599717 0.85 L3MBTL1 (0.59) S100A4PTPRCMAPK1MAPTTDP1
SCHEMBL11306687 0.85 MAPT (0.71) PTPRCMAPK1MAPTTDP1ALDH1A1
SCHEMBL42481 0.85 MAPT (0.71) PTPRCMAPK1MAPTTDP1ALDH1A1
SCHEMBL29438168 0.85 MAPT (0.71) PTPRCMAPK1MAPTTDP1ALDH1A1
SCHEMBL156735 0.83 S100A4 (0.79) S100A4PTPRCMAPK1MAPTTDP1
Anthraquinone SCHEMBL27736010 0.83 S100A4 (0.79) S100A4PTPRCMAPK1MAPTTDP1
SCHEMBL28401690 0.82 EPAS1 (0.45) S100A4PTPRCMAPK1MAPTTDP1
Water SCHEMBL11135902 0.82 S100A4 (0.77) S100A4PTPRCMAPK1MAPTTDP1
Ammonia Solution, Strong SCHEMBL27539963 0.82 S100A4 (0.77) S100A4PTPRCMAPK1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4082778-A ANTHRAQUINONE DYES, ORGANIC PIGMENTS CIBA-GEIGY CORPORATION (US) 1978-04-04 US disclosed