SCHEMBL28401690

SCHEMBL28401690

O=C1c2c(Nc3ccccc3[N+](=O)[O-])cccc2C(=O)c2c(F)c(F)cc(F)c21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPAS1 Q99814 1/20 0.45
S100A4 P26447 2/20 0.45
PTPRC P08575 1/20 0.45
MAPK1 P28482 7/20 0.43
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
ALDH1A1 P00352 2/20 0.43
CASP7 P55210 1/20 0.43
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A1 P68400 1/20 0.42
CSNK2A3 Q8NEV1 1/20 0.42
MAPT P10636 6/20 0.39
POLB P06746 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
APEX1 P27695 1/20 0.39
CASP6 P55212 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11650656 0.82 S100A4 (0.61) EPAS1S100A4PTPRCMAPK1TDP1
SCHEMBL28400097 0.79 CYP1A2 (0.39) MAPK1TDP1L3MBTL1ALDH1A1MAPT
SCHEMBL6653775 0.76 MAPT (0.50) EPAS1S100A4PTPRCMAPK1TDP1
SCHEMBL29502787 0.76 MAPT (0.50) EPAS1S100A4PTPRCMAPK1TDP1
SCHEMBL4054385 0.73 MAPK1 (0.57) EPAS1MAPK1TDP1L3MBTL1ALDH1A1
SCHEMBL11622598 0.73 MAPT (0.61) S100A4PTPRCMAPK1TDP1L3MBTL1
SCHEMBL29378153 0.72 TTR (0.50) S100A4PTPRCMAPK1TDP1L3MBTL1
SCHEMBL11599717 0.72 L3MBTL1 (0.59) EPAS1S100A4PTPRCMAPK1TDP1
SCHEMBL3571014 0.71 MAPK1 (0.62) EPAS1MAPK1TDP1L3MBTL1ALDH1A1
SCHEMBL7930683 0.71 CYP3A4 (0.56) EPAS1MAPK1TDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113661065-B Resin composition, molded body, optical layer, cover member, and moving body 住友电木株式会社 2022-05-10 CN disclosed
CN-113661065-A Resin composition, molded body, optical layer, cover member, and moving body 住友电木株式会社 2021-11-16 CN disclosed
CN-111630121-B Resin composition, optical layer, cover member, and moving object 住友电木株式会社 2021-09-07 CN disclosed
CN-113302525-A Optical sheet and optical element 住友电木株式会社 2021-08-24 CN disclosed
CN-111630121-A Resin composition, optical layer, cover member, and moving object 住友电木株式会社 2020-09-04 CN disclosed
CN-111164467-A Optical sheet and optical element 住友电木株式会社 2020-05-15 CN disclosed