SCHEMBL1165191

SCHEMBL1165191

Clc1ccc(/N=C/c2cccc(/C=N/c3ccc(Cl)cc3Cl)n2)c(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
MAPT P10636 5/20 0.43
ALDH1A1 P00352 4/20 0.43
POLB P06746 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HTT P42858 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CYP1A2 P05177 1/20 0.43
HSP90AA1 P07900 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
HPGD P15428 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GUSB P08236 1/20 0.38
TERT O14746 1/20 0.37
ITGB3 P05106 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1165194 1.00 LMNA (0.47) LMNAMAPTALDH1A1POLBKDM4E
SCHEMBL28374239 0.98 LMNA (0.46) LMNAMAPTALDH1A1POLBKDM4E
Hydrochloric Acid SCHEMBL39691 0.97 LMNA (0.44) LMNAMAPTALDH1A1POLBKDM4E
Hydrochloric Acid SCHEMBL39690 0.97 LMNA (0.44) LMNAMAPTALDH1A1POLBKDM4E
SCHEMBL29695684 0.95 LMNA (0.43) LMNAMAPTALDH1A1POLBKDM4E
SCHEMBL31502197 0.77 CHRM5 (0.58) LMNAMAPTALDH1A1POLBKDM4E
SCHEMBL11405980 0.75 LMNA (0.49) LMNAMAPTALDH1A1POLBKDM4E
SCHEMBL11405992 0.75 LMNA (0.49) LMNAMAPTALDH1A1POLBKDM4E
SCHEMBL30374604 0.75 LMNA (0.49) LMNAMAPTALDH1A1POLBKDM4E
SCHEMBL4972488 0.74 LMNA (0.51) LMNAMAPTALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2746320-A1 Polyethylene composition having high mechanical properties Basell Polyolefine GmbH (DE) 2014-06-25 EP disclosed
EP-2467409-A1 POLYETHYLENE FOR ROTOMOULDING Basell Polyolefine GmbH (DE) 2012-06-27 EP disclosed
EP-2467407-A1 POLYETHYLENE FOR ROTOMOULDING Basell Polyolefine GmbH (DE) 2012-06-27 EP disclosed
WO-2011020620-A1 POLYETHYLENE FOR ROTOMOULDING BASELL POLYOLEFINE GMBH (DE) 2011-02-24 WO disclosed
WO-2011020621-A1 POLYETHYLENE FOR ROTOMOULDING BASELL POLYOLEFINE GMBH (DE) 2011-02-24 WO disclosed
EP-2134801-A2 ADHESIVE POLYMER COMPOSITION Basell Polyolefine GmbH (DE) 2009-12-23 EP disclosed
WO-2009103516-A2 ADHESIVE POLYMER COMPOSITION BASELL POLYOLEFINE GMBH (DE) 2009-08-27 WO disclosed