Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL39690 | 1.00 | LMNA (0.44) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL1165191 | 0.97 | LMNA (0.47) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL1165194 | 0.97 | LMNA (0.47) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL28374239 | 0.95 | LMNA (0.46) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL29695684 | 0.92 | LMNA (0.43) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL31502197 | 0.75 | CHRM5 (0.58) | LMNAMAPTALDH1A1POLBKDM4E | |
| Hydrochloric Acid SCHEMBL39915 | 0.74 | LMNA (0.36) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL30374604 | 0.73 | LMNA (0.49) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL11405992 | 0.73 | LMNA (0.49) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL11405980 | 0.73 | LMNA (0.49) | LMNAMAPTALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12415911-B2 | Polyethylene composition for filaments or fibers | BASELL POLYOLEFINE GMBH (DE) | 2025-09-16 | — | — | US | disclosed |
| US-11999839-B2 | Polyethylene composition for filaments or fibers | BASELL POLYOLEFINE GMBH (DE) | 2024-06-04 | — | — | US | disclosed |
| EP-4069775-B1 | POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS | BASELL POLYOLEFINE GMBH (DE) | 2024-04-03 | — | — | EP | disclosed |
| EP-4069774-B1 | POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS | BASELL POLYOLEFINE GMBH (DE) | 2024-01-17 | — | — | EP | disclosed |
| US-20230075830-A1 | POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS | BASELL POLYOLEFINE GMBH (DE) | 2023-03-09 | — | — | US | disclosed |
| US-20230002598-A1 | POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS | BASELL POLYOLEFINE GMBH (DE) | 2023-01-05 | — | — | US | disclosed |
| US-11466144-B2 | Polyethylene composition having high mechanical properties | BASELL POLYOLEFINE GMBH (DE) | 2022-10-11 | — | — | US | disclosed |
| EP-2935414-B2 | POLYETHYLENE COMPOSITION HAVING HIGH MECHANICAL PROPERTIES | BASELL POLYOLEFINE GMBH (DE) | 2021-11-17 | — | — | EP | disclosed |
| WO-2021110769-A1 | POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS | BASELL POLYOLEFINE GMBH (DE) | 2021-06-10 | — | — | WO | disclosed |
| EP-2760958-B1 | SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES | EQUISTAR CHEM LP (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-2326678-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | Basell Polyolefine GmbH (DE) | 2011-06-01 | — | — | EP | disclosed |
| EP-2322565-A2 | Catalyst composition for the preparation of polyethylene | Basell Polyolefine GmbH (DE) | 2011-05-18 | — | — | EP | disclosed |
| US-20110045295-A1 | ADHESIVE POLYMER COMPOSITION | BASELL POLYOLEFINE GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2236577-A2 | Polyethylene composition | Basell Polyolefine GmbH (DE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2010034461-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010034508-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010034464-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010034520-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010034463-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| US-20080286509-A1 | Polyethylene and Catalyst Composition for Its Preparation | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |