Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434561 | 0.78 | — | — | |
| SCHEMBL10503374 | 0.78 | — | — | |
| SCHEMBL9056681 | 0.77 | TSHR (0.55) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL4489250 | 0.76 | — | — | |
| SCHEMBL8721877 | 0.74 | — | — | |
| SCHEMBL10502953 | 0.72 | TSHR (0.64) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL3496247 | 0.72 | LMNA (0.54) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL3168163 | 0.71 | TSHR (0.45) | TSHRALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL15358845 | 0.70 | — | — | |
| SCHEMBL7724048 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130554-A | ANTISECRETORY, GROWTH INHIBITORS, LOWER BLOOD GLUCOSE | MERCK & CO., INC. (US) | 1978-12-19 | — | — | US | claimed |