⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056681 | 0.82 | TSHR (0.55) | — | |
| SCHEMBL15358845 | 0.80 | — | — | |
| SCHEMBL15434561 | 0.79 | — | — | |
| SCHEMBL8721877 | 0.79 | — | — | |
| SCHEMBL13911570 | 0.79 | TSHR (0.82) | — | |
| SCHEMBL3496247 | 0.77 | LMNA (0.54) | — | |
| SCHEMBL10502953 | 0.77 | TSHR (0.64) | — | |
| SCHEMBL9312739 | 0.76 | TSHR (0.61) | — | |
| SCHEMBL11652116 | 0.76 | TSHR (0.45) | — | |
| SCHEMBL3168163 | 0.76 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093425-A1 | TRANSDUCIBLE DELIVERY OF NUCLEIC ACIDS BY REVERSIBLE PHOSPHOTRIESTER CHARGE NEUTRALIZATION PROTECTING GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093425-A1 | TRANSDUCIBLE DELIVERY OF NUCLEIC ACIDS BY REVERSIBLE PHOSPHOTRIESTER CHARGE NEUTRALIZATION PROTECTING GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093425-A1 | TRANSDUCIBLE DELIVERY OF NUCLEIC ACIDS BY REVERSIBLE PHOSPHOTRIESTER CHARGE NEUTRALIZATION PROTECTING GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-09 | — | — | US | disclosed |