Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BHMT | Q93088 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3168163 | 0.81 | TSHR (0.45) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL25749262 | 0.79 | KMT2A (0.50) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL9056681 | 0.78 | TSHR (0.55) | KMT2ATSHRADRA1AALDH1A1KDM4E | |
| SCHEMBL4489250 | 0.77 | — | — | |
| SCHEMBL8599981 | 0.77 | CYP2D6 (0.50) | KMT2AHSD17B10TSHRADRA1AALDH1A1 | |
| E388 SCHEMBL27633254 | 0.76 | LMNA (0.82) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL8721877 | 0.76 | — | — | |
| SCHEMBL15434561 | 0.76 | — | — | |
| SCHEMBL17030027 | 0.75 | LMNA (0.50) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL18668770 | 0.75 | BHMT (0.54) | BHMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437233-B | Directional synthesis method of polypeptide dimer | 湖北健翔生物制药有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-114437233-A | Directional synthesis method of polypeptide dimer | 湖北健翔生物制药有限公司 | 2022-05-06 | — | — | CN | disclosed |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-06-03 | — | — | US | disclosed |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-06-03 | — | — | US | disclosed |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-06-03 | — | — | US | disclosed |
| US-5376635-A | A polypeptides as diuretics, hypotensive agents | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-12-27 | — | — | US | disclosed |
| EP-0283956-B1 | FLUORINE CONTAINING ATRIAL NATRIURETIC PEPTIDES | BIO-MEGA INC. (CA) | 1992-11-11 | — | — | EP | disclosed |
| US-5095004-A | Hypotensives, diuretics | BIO-MEGA INC. (CA) | 1992-03-10 | — | — | US | disclosed |
| EP-0283956-A2 | Fluorine containing atrial natriuretic peptides | BIO-MEGA INC. (CA) | 1988-09-28 | — | — | EP | disclosed |
| US-4130554-A | ANTISECRETORY, GROWTH INHIBITORS, LOWER BLOOD GLUCOSE | MERCK & CO., INC. (US) | 1978-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | TNFRSF1A, TNFRSF9, CD40 | LMNA 3111/4885KMT2A 4303/4885HSD17B10 3338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.