Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 10/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920635 | 0.95 | TDP1 (0.59) | LTB4RKCNA3TDP1HPGDL3MBTL1 | |
| SCHEMBL1716121 | 0.89 | MAPK1 (0.53) | KCNA3TDP1HPGDL3MBTL1ALOX5 | |
| SCHEMBL1803119 | 0.87 | RAB9A (0.55) | L3MBTL1ALOX5PPARGPPARA | |
| SCHEMBL1801997 | 0.85 | LTB4R (0.57) | LTB4RTDP1HPGDRARBL3MBTL1 | |
| SCHEMBL5514899 | 0.84 | TDP1 (0.63) | KCNA3TDP1HPGDL3MBTL1ALOX5 | |
| SCHEMBL4756791 | 0.82 | TDP1 (0.61) | KCNA3TDP1L3MBTL1PPARGPPARA | |
| SCHEMBL5508343 | 0.82 | TDP1 (0.61) | KCNA3TDP1L3MBTL1PPARGPPARA | |
| SCHEMBL1083669 | 0.81 | TDP1 (0.49) | KCNA3TDP1HPGDRARBL3MBTL1 | |
| SCHEMBL1064263 | 0.81 | TDP1 (0.49) | KCNA3TDP1HPGDRARBL3MBTL1 | |
| SCHEMBL10933261 | 0.81 | KCNA3 (0.57) | KCNA3TDP1HPGDL3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097496-A | ANTIPROSTAGLANDIN ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
| US-4083990-A | ANTIPROSTAGLANDIN EFFECT | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-3984459-A | ANTI-PROSTAGLANDINS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-10-05 | — | — | US | disclosed |