Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652148 | 0.95 | LTB4R (0.56) | TDP1HPGDKCNA3L3MBTL1LTB4R | |
| SCHEMBL1716121 | 0.91 | MAPK1 (0.53) | TDP1HPGDKCNA3L3MBTL1PPARG | |
| SCHEMBL5523873 | 0.83 | TDP1 (0.70) | TDP1HPGDKCNA3L3MBTL1PPARG | |
| SCHEMBL1803119 | 0.82 | RAB9A (0.55) | L3MBTL1PPARGPPARAALOX5RAB9A | |
| SCHEMBL1801997 | 0.80 | LTB4R (0.57) | TDP1HPGDL3MBTL1LTB4RMTNR1A | |
| SCHEMBL5133482 | 0.80 | TDP1 (0.57) | TDP1HPGDKCNA3L3MBTL1PPARG | |
| SCHEMBL15866588 | 0.79 | LMNA (0.62) | PPARGPPARAMTNR1AMTNR1BLMNA | |
| SCHEMBL787266 | 0.79 | LMNA (0.62) | PPARGPPARAMTNR1AMTNR1BLMNA | |
| SCHEMBL31032939 | 0.79 | LMNA (0.62) | PPARGPPARAMTNR1AMTNR1BLMNA | |
| SCHEMBL7449489 | 0.79 | KCNA3 (0.62) | TDP1HPGDKCNA3RECQLMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020408-A1 | INDOLES HAVING ANTI-DIABETIC ACTIVITY | MERCK & CO., INC. (US) | 2004-03-11 | — | — | WO | disclosed |