Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11655156 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2ARAB9AKDM4E | |
| SCHEMBL11655212 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1LMNAKMT2ARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11655456 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1LMNAKMT2ARAB9AKDM4E | |
| SCHEMBL11657715 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2ARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11659587 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAKMT2ARAB9AKDM4E | |
| SCHEMBL11653881 | 0.78 | KMT2A (0.45) | ALDH1A1KMT2AMAPTMEN1HPGD | |
| SCHEMBL11661309 | 0.77 | S100B (0.44) | NOS3NOX1ALDH1A1KMT2ARAB9A | |
| SCHEMBL11662468 | 0.77 | CYP2C9 (0.47) | ALDH1A1PLK1LMNAKMT2AKDM4E | |
| SCHEMBL11659361 | 0.76 | MAPT (0.40) | NOS3NOS1ALDH1A1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL11654418 | 0.75 | MAPT (0.40) | NOS3NOS1ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073636-A | Azolylamidine compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |
| US-3993469-A | Azolylamidine compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |