Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11655456 | 0.98 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL11655156 | 0.86 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL11657715 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AMAPTHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL11659587 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL11658191 | 0.81 | KMT2A (0.65) | KMT2AMAPTTDP1POLBTSHR | |
| SCHEMBL11652170 | 0.81 | NOS3 (0.40) | SMN1; SMN2KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL11662468 | 0.81 | CYP2C9 (0.47) | KMT2AMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL11661309 | 0.81 | S100B (0.44) | SMN1; SMN2KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL11659361 | 0.80 | MAPT (0.40) | MAPTCYP1A2CYP2C19ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL11661831 | 0.80 | KMT2A (0.63) | KMT2AMAPTTDP1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073636-A | Azolylamidine compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |
| US-3993469-A | Azolylamidine compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |