Ether

Ether

SCHEMBL11652175

CCOCC.N#CNC(N)=O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.36
ALDH1A1 P00352 4/20 0.32
TSHR P16473 2/20 0.32
MCL1 Q07820 2/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CAD P27708 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX12 P18054 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100367 0.81
SCHEMBL17476091 0.78
Ether SCHEMBL11649270 0.74 TSHR (0.56) ALOX15ALDH1A1TSHRMGAMGAA
Ether SCHEMBL1011439 0.72
Ether SCHEMBL7127103 0.71 ALOX15 (0.52) ALOX15ALDH1A1TSHRMGAMGAA
Ether SCHEMBL173703 0.70
Ether SCHEMBL442290 0.70
Urethane SCHEMBL28022627 0.69 ALOX15 (0.58) ALOX15ALDH1A1TSHRMGAMGAA
Carbonyl Cyanide SCHEMBL9417595 0.69 ALDH1A1 (0.43) ALOX15ALDH1A1TSHRMCL1MGAM
SCHEMBL10885996 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US claimed
US-4031067-A Polytriazines and a process for their production BAYER AKTIENGESELLSCHAFT (DT) 1977-06-21 US claimed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed
US-4059567-A High molecular weight polytriazines of soluble polymeric N-cyano-isourea ethers BAYER AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed
US-4031067-A Polytriazines and a process for their production BAYER AKTIENGESELLSCHAFT (DT) 1977-06-21 US disclosed