⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL1011439 | 0.90 | — | — | |
| Ether SCHEMBL173703 | 0.87 | — | — | |
| Ether SCHEMBL9353265 | 0.86 | ALDH1A1 (0.52) | — | |
| Ether SCHEMBL7531159 | 0.86 | ALDH1A1 (0.52) | — | |
| Ether SCHEMBL164114 | 0.86 | — | — | |
| Ether SCHEMBL3336965 | 0.86 | ALDH1A1 (0.52) | — | |
| Ether SCHEMBL1234081 | 0.86 | ALDH1A1 (0.52) | — | |
| Ether SCHEMBL7021309 | 0.84 | ALOX15 (0.48) | — | |
| Ether SCHEMBL4173483 | 0.84 | — | — | |
| Propionamide SCHEMBL28035985 | 0.84 | ALOX15 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372531-A | The ethers acetamide derivative of the amide structure containing alpha-carbonyl and its application | 贵州大学 | 2019-10-25 | — | — | CN | claimed |
| CN-110372531-A | The ethers acetamide derivative of the amide structure containing alpha-carbonyl and its application | 贵州大学 | 2019-10-25 | — | — | CN | disclosed |
| CN-110372531-A | The ethers acetamide derivative of the amide structure containing alpha-carbonyl and its application | 贵州大学 | 2019-10-25 | — | — | CN | disclosed |
| CN-110372531-A | The ethers acetamide derivative of the amide structure containing alpha-carbonyl and its application | 贵州大学 | 2019-10-25 | — | — | CN | disclosed |
| CN-109438336-A | A kind of preparation method of Rui Gefeini hydrate | 广东安诺药业股份有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-107205970-A | Immunomodulator | 弗莱塞斯生物科学公司 | 2017-09-26 | — | — | CN | disclosed |
| US-8618311-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2013-12-31 | — | — | US | disclosed |
| US-20130090483-A1 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2013-04-11 | — | — | US | disclosed |
| US-8344162-B2 | Synthetic processes for the preparation of aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2013-01-01 | — | — | US | disclosed |
| US-20120271057-A9 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2012-10-25 | — | — | US | disclosed |
| EP-0831851-B1 | USE OF PSEUDOPTEROSINS FOR PROMOTING WOUND HEALING | NEXELL THERAPEUTICS INC (US) | 2002-11-20 | — | — | EP | disclosed |
| CN-1254346-A | Calcitonin receptor-binding peptides | DIATIDE INC (US) | 2000-05-24 | — | — | CN | disclosed |
| US-6022862-A | Use of pseudopterosins for promoting wound healing | VIMRX PHARMACEUTICALS, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0835117-A4 | ETHER DERIVATIVES OF PSEUDOPTEROSIN | UNIV CALIFORNIA (US) | 1999-07-21 | — | — | EP | disclosed |
| EP-0835117-A1 | ETHER DERIVATIVES OF PSEUDOPTEROSIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-15 | — | — | EP | disclosed |
| EP-0831851-A1 | USE OF PSEUDOPTEROSINS FOR PROMOTING WOUND HEALING | Osteoarthritis Sciences, Inc. (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5624911-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-04-29 | — | — | US | disclosed |
| US-5597808-A | Use of pseudopterosins for promoting wound healing | OSTEOARTHRITIS SCIENCES, INCORPORATED (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1996040161-A1 | ETHER DERIVATIVES OF PSEUDOPTEROSIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040160-A1 | USE OF PSEUDOPTEROSINS FOR PROMOTING WOUND HEALING | OSTEOARTHRITIS SCIENCES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |