Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683100 | 0.81 | MEN1 (0.49) | HPGDALDH1A1MPOSMN1; SMN2GAA | |
| SCHEMBL16513295 | 0.81 | SMN1; SMN2 (0.51) | HPGDMPOP2RX7SMN1; SMN2GAA | |
| SCHEMBL13696436 | 0.80 | ALDH1A1 (0.46) | HPGDKDM4EALDH1A1HSD17B10PDE7A | |
| SCHEMBL22518630 | 0.80 | LRRK2 (0.43) | HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL13696435 | 0.78 | ALDH1A1 (0.44) | HPGDKDM4EALDH1A1HSD17B10PDE7A | |
| SCHEMBL1811782 | 0.78 | HPGD (0.44) | HPGDKDM4EALDH1A1HSD17B10PDE7A | |
| SCHEMBL12335150 | 0.77 | HPGD (0.58) | HPGDKDM4EALDH1A1HSD17B10PDE7A | |
| SCHEMBL1814476 | 0.76 | HPGD (0.47) | HPGDKDM4EALDH1A1HSD17B10PDE7A | |
| SCHEMBL5349678 | 0.73 | ALDH1A1 (0.41) | HPGDKDM4EALDH1A1HSD17B10PDE7A | |
| SCHEMBL1695102 | 0.72 | KDM4E (0.50) | HPGDKDM4EALDH1A1HSD17B10PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108982-A | DIURETICS, HYPOTENSIVE AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1978-08-22 | — | — | US | disclosed |