Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652181 | 0.81 | HPGD (0.50) | ALDH1A1MAPTALOX15TDP1HPGD | |
| SCHEMBL26621173 | 0.79 | ALDH1A1 (0.41) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL16513295 | 0.79 | SMN1; SMN2 (0.51) | ALOX15HPGDMPONR3C1SMN1; SMN2 | |
| SCHEMBL28746213 | 0.77 | NSD3 (0.39) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL29683420 | 0.73 | PKM (0.39) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL22518630 | 0.73 | LRRK2 (0.43) | ALDH1A1HPGDCDK2NR3C1SRC | |
| Hydrochloric Acid SCHEMBL22518638 | 0.72 | PKM (0.38) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL24196837 | 0.70 | SRC (0.54) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL29683599 | 0.70 | IGF1R (0.38) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL11960827 | 0.69 | MEN1 (0.37) | MEN1ALDH1A1MAPTPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591324-A | Pyrazinone derivatives, preparation and application thereof | 深圳微芯生物科技股份有限公司 | 2022-06-07 | — | — | CN | disclosed |