Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656137 | 0.87 | PARP2 (0.50) | PARP15TNKS2PARP2EGLN2CHEK1 | |
| SCHEMBL11648560 | 0.80 | HSP90AA1 (0.33) | PARP15TNKS2PARP2MAP4K4DYRK1A | |
| SCHEMBL11650673 | 0.80 | PARP10 (0.50) | PARP15TNKS2PARP2EGLN2KDM4E | |
| SCHEMBL28173725 | 0.80 | PIM1 (0.46) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL11652353 | 0.75 | ALDH1A1 (0.53) | TNKS2PARP2CHEK1PDGFRADYRK1A | |
| SCHEMBL11652422 | 0.67 | PARP2 (0.54) | PARP15TNKS2PARP2KDM4EALDH1A1 | |
| SCHEMBL16441919 | 0.64 | RAB9A (0.48) | KDM4EALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL406465 | 0.62 | CUL4A (0.59) | EGLN2CHEK1AURKADAPK3JAK2 | |
| SCHEMBL11737589 | 0.62 | SMN1; SMN2 (0.46) | CHEK1DYRK1ACLK4KDM4EALDH1A1 | |
| SCHEMBL23076418 | 0.62 | RAB9A (0.47) | PARP15TNKS2PARP2TMEM97KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075218-A | INSECTICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3974286-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1976-08-10 | — | — | US | disclosed |