Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 5/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651190 | 0.76 | EGLN2 (0.40) | PARP15PARP10TNKS2PTGS2EGLN2 | |
| SCHEMBL11653345 | 0.76 | EGLN2 (0.40) | MEN1KMT2ANPSR1PTGS2HPGD | |
| SCHEMBL11651246 | 0.76 | PARP15 (0.54) | PARP15PARP10TNKS2MEN1KMT2A | |
| SCHEMBL11651046 | 0.75 | PARP15 (0.52) | PARP15PARP10TNKS2MEN1KMT2A | |
| SCHEMBL11653443 | 0.74 | MAPT (0.35) | PARP15PARP10TNKS2MEN1KMT2A | |
| SCHEMBL11652666 | 0.71 | PARP15 (0.51) | PARP15PARP10TNKS2MEN1KMT2A | |
| SCHEMBL25323644 | 0.70 | TNKS2 (1.00) | PARP15PARP10TNKS2KDM4EPARP2 | |
| SCHEMBL11652353 | 0.68 | ALDH1A1 (0.53) | TNKS2MEN1KMT2ANPSR1PTGS2 | |
| SCHEMBL4614153 | 0.65 | PARP15 (0.48) | PARP15PARP10TNKS2MEN1KMT2A | |
| SCHEMBL4614857 | 0.61 | NPSR1 (0.47) | PARP15PARP10TNKS2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075218-A | INSECTICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | claimed |
| US-4075218-A | INSECTICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3974286-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1976-08-10 | — | — | US | disclosed |