Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 7/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653345 | 0.80 | EGLN2 (0.40) | EGLN2PTGS2PKMPTGS1LMNA | |
| SCHEMBL11652662 | 0.76 | PARP15 (0.54) | EGLN2PTGS2PKMPARP15TNKS2 | |
| SCHEMBL11653443 | 0.74 | MAPT (0.35) | PTGS2PKMPTGS1PARP15TNKS2 | |
| SCHEMBL11648344 | 0.73 | EGLN2 (0.40) | EGLN2PTGS2PKMPTGS1LMNA | |
| SCHEMBL11652353 | 0.72 | ALDH1A1 (0.53) | PTGS2PKMPTGS1TNKS2PARP2 | |
| SCHEMBL11649318 | 0.71 | PTGS2 (0.39) | PTGS2PARP15TNKS2PARP2PARP10 | |
| SCHEMBL17621076 | 0.62 | PTGER1 (0.39) | PTGS2PTGS1PARP15TNKS2PARP2 | |
| SCHEMBL11650673 | 0.60 | PARP10 (0.50) | EGLN2PTGS2PARP15TNKS2PARP2 | |
| SCHEMBL11652215 | 0.60 | PARP15 (0.40) | EGLN2PTGS2PTGS1PARP15TNKS2 | |
| SCHEMBL17181375 | 0.56 | MIF (0.38) | LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974286-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1976-08-10 | — | — | US | claimed |
| US-4075218-A | INSECTICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3974286-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1976-08-10 | — | — | US | disclosed |