Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601247 | 0.88 | KMT2A (0.50) | MAPTKMT2AALOX15CYP1A2CYP2C9 | |
| SCHEMBL11601679 | 0.84 | NPC1 (0.41) | MAPTKMT2AALOX15GAAALDH1A1 | |
| SCHEMBL11599847 | 0.83 | MAPT (0.49) | MAPTKMT2AALOX15GAAALDH1A1 | |
| SCHEMBL11601121 | 0.79 | LMNA (0.56) | MAPTKMT2AALOX15GAAALDH1A1 | |
| SCHEMBL13182693 | 0.78 | ALDH1A1 (0.47) | MAPTKMT2ACYP1A2CYP2C9GAA | |
| SCHEMBL3416368 | 0.76 | SMN1; SMN2 (0.43) | MAPTKMT2AALOX15KDM4EMEN1 | |
| SCHEMBL27682646 | 0.76 | SMN1; SMN2 (0.43) | MAPTKMT2AALOX15CYP1A2HPGD | |
| SCHEMBL11602961 | 0.76 | MAPT (0.54) | MAPTKMT2AALOX15CYP2C9PKM | |
| SCHEMBL11602902 | 0.76 | MAPT (0.57) | MAPTKMT2ACYP1A2CYP2C9GAA | |
| SCHEMBL25476901 | 0.76 | ALDH1A1 (0.36) | MAPTKMT2AALOX15HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070536-A | Process for the preparation of 4-benzoylpyrazole derivatives | SANKYO COMPANY LIMITED (JA) | 1978-01-24 | — | — | US | disclosed |