Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657906 | 0.76 | IDO1 (0.50) | HPGDKMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL11865348 | 0.71 | HTT (0.51) | HPGDKMT2AMEN1MITFTSHR | |
| SCHEMBL10981879 | 0.71 | KMT2A (0.50) | HPGDKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL11657752 | 0.68 | IDO1 (0.56) | KMT2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL9035361 | 0.65 | HPGD (0.57) | HPGDKMT2AMEN1MITFTSHR | |
| SCHEMBL1286277 | 0.65 | FFAR1 (0.65) | HPGDKMT2AMEN1MITFTSHR | |
| SCHEMBL3927340 | 0.65 | HPGD (0.53) | HPGDKMT2AMEN1MITFTSHR | |
| SCHEMBL11664604 | 0.64 | SMN1; SMN2 (0.53) | HPGDKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL28024949 | 0.64 | MAPT (0.47) | HPGDKMT2AMEN1MITFTSHR | |
| SCHEMBL11218295 | 0.63 | KMT2A (0.54) | HPGDKMT2AMEN1MITFTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | disclosed |