Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661930 | 0.82 | IDO1 (0.50) | IDO1L3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11656567 | 0.81 | IDO1 (0.53) | IDO1L3MBTL1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11657752 | 0.77 | IDO1 (0.56) | IDO1ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL11654331 | 0.76 | HPGD (0.47) | TDP1L3MBTL1LMNAALDH1A1RAB9A | |
| SCHEMBL8345822 | 0.75 | TDP1 (0.62) | IDO1TDP1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL11664604 | 0.74 | SMN1; SMN2 (0.53) | IDO1LMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11359685 | 0.73 | EPHX1 (0.51) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11842725 | 0.73 | TDP1 (0.61) | IDO1TDP1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL14611678 | 0.73 | IDO1 (0.57) | IDO1TDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL6689595 | 0.73 | IDO1 (0.68) | IDO1TDP1L3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | disclosed |