Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657671 | 0.83 | CRBN (0.47) | MAPTCYP2C9CYP2C19HSD17B10DDB1 | |
| SCHEMBL15347584 | 0.81 | SMN1; SMN2 (0.47) | MAPTHPGDALDH1A1ALOX15LMNA | |
| SCHEMBL15152744 | 0.81 | SMN1; SMN2 (0.47) | MAPTHPGDALDH1A1ALOX15LMNA | |
| SCHEMBL5273038 | 0.77 | MAPT (0.45) | MAPTAKR1C3CYP2C9CYP2C19HPGD | |
| SCHEMBL29695938 | 0.74 | MAOA (0.58) | MAPTCYP2C9CYP2C19DDB1CRBN | |
| SCHEMBL7479814 | 0.73 | ATF4 (0.40) | MAPTNOTUMDDB1CRBNHPGD | |
| SCHEMBL918204 | 0.73 | NPC1 (0.66) | MAPTNOTUMAKR1C3CYP2C9HPGD | |
| SCHEMBL894800 | 0.73 | MGLL (0.60) | MAPTLMNAKMT2AMEN1 | |
| SCHEMBL894802 | 0.73 | MGLL (0.60) | MAPTLMNAKMT2AMEN1 | |
| SCHEMBL637532 | 0.73 | NPC1 (0.66) | MAPTNOTUMAKR1C3CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103108866-B | cyclohexane derivative compound | DAIICHI SANKYO Co.,Ltd. (JP) | 2015-09-09 | — | — | CN | disclosed |