Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657752 | 0.82 | IDO1 (0.56) | IDO1HTTPOLBCYP3A4CYP2C19 | |
| SCHEMBL11350994 | 0.79 | HPGD (0.54) | HTTHPGDPOLBCYP2C19KMT2A | |
| SCHEMBL27592486 | 0.77 | LMNA (0.68) | SMN1; SMN2LMNAIDO1HTTTAAR1 | |
| SCHEMBL11657906 | 0.74 | IDO1 (0.50) | SMN1; SMN2LMNAIDO1HPGDPOLB | |
| SCHEMBL11656567 | 0.73 | IDO1 (0.53) | SMN1; SMN2LMNAIDO1TAAR1KMT2A | |
| SCHEMBL3761179 | 0.73 | CTBP2 (0.50) | LMNAHTTHPGDCYP3A4CYP2C19 | |
| SCHEMBL12835100 | 0.71 | TAAR1 (0.59) | SMN1; SMN2LMNAIDO1HTTTAAR1 | |
| SCHEMBL29034446 | 0.71 | HTT (0.59) | SMN1; SMN2LMNAIDO1HTTTAAR1 | |
| SCHEMBL29620133 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAIDO1HTTTAAR1 | |
| SCHEMBL66777 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAIDO1HTTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | disclosed |