Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | CFTR | P13569 | 6/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450818 | 1.00 | ALDH1A1 (0.77) | ALDH1A1ATMCFTRGPR84GABRA1 | |
| SCHEMBL117198 | 0.87 | ALDH1A1 (1.00) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL27785298 | 0.87 | ALDH1A1 (1.00) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL29544426 | 0.87 | ALDH1A1 (1.00) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| Hydrochloric Acid SCHEMBL28283888 | 0.85 | ALDH1A1 (0.96) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| Hydrochloric Acid SCHEMBL28283733 | 0.85 | ALDH1A1 (0.96) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| Hydrochloric Acid SCHEMBL7400951 | 0.85 | ALDH1A1 (0.96) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| Hydrochloric Acid SCHEMBL29715885 | 0.85 | ALDH1A1 (0.96) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL377150 | 0.84 | CFTR (0.67) | ALDH1A1ATMCFTRGPR84GABRA1 | |
| SCHEMBL29551347 | 0.84 | CFTR (0.67) | ALDH1A1ATMCFTRGPR84GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2819670-B1 | PHARMACEUTICAL COMPOSITION AND ADMINISTRATION THEREOF | VERTEX PHARMA (US) | 2026-05-20 | — | — | EP | claimed |
| CN-116410180-B | 4-Oxo quinoline-3-carboxamide derivative and application thereof | 青岛大学 | 2024-09-10 | — | — | CN | claimed |
| CN-117673514-A | Neutral dispergator and preparation method and application thereof | 江苏长能节能新材料科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-116410180-A | 4-oxo quinoline-3-carboxamide derivative and application thereof | 青岛大学 | 2023-07-11 | — | — | CN | claimed |
| US-20230089351-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2023-03-23 | — | — | US | claimed |
| WO-2021158573-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | claimed |
| WO-2021158575-A1 | COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2021-08-12 | — | — | WO | claimed |
| CN-108948014-A | 1- aryl -4- Oxy-1, the preparation and application of the pyrido heterocycle compound of 4- dihydroquinoline structure | 江西科技师范大学 | 2018-12-07 | — | — | CN | claimed |
| EP-2509954-A1 | 4 -OXO- 1H -QUINOLINE- 3 - CARBOXAMIDES AS MODULATORS OF ATP -BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2012-10-17 | — | — | EP | claimed |
| WO-2011072241-A1 | 4 -OXO- IH -QUINOLINE- 3 - CARBOXAMIDES AS MODULATORS OF ATP -BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-16 | — | — | WO | claimed |
| EP-1140851-A1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | claimed |
| EP-1080092-A2 | BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 2001-03-07 | — | — | EP | claimed |
| WO-2000040563-A1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | claimed |
| WO-1999061444-A2 | BICYCLIC PYRIMIDINES AND BICYCLIC 3,4-DIHYDROPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1999-12-02 | — | — | WO | claimed |
| EP-4648753-A1 | COMPOSITIONS FOR THE TREATMENT OF CFTR-MEDIATED DISEASES | Vertex Pharmaceuticals Incorporated (US) | 2025-11-19 | — | — | EP | disclosed |
| US-12458635-B2 | Pharmaceutical composition and administrations thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-11-04 | — | — | US | disclosed |
| WO-2025171098-A1 | COMPOSITIONS FOR THE TREATMENT OF CFTR-MEDIATED DISEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-08-14 | — | — | WO | disclosed |
| EP-0230143-B1 | PHOTODEGRADING AGENT, PHOTODEGRADABLE ETHYLENE POLYMER COMPOSITIONS AND ARTICLES PRODUCED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1989-11-15 | — | — | EP | disclosed |
| US-4835163-A | N-alkoxyalkyl derivatives of quinolone carboxamides | SANOFI (FR) | 1989-05-30 | — | — | US | disclosed |
| US-4835163-A | N-alkoxyalkyl derivatives of quinolone carboxamides | SANOFI (FR) | 1989-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230089351-A1 | METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | FABP2, FABP4, GUSB | ALDH1A1 2722/4885ATM 3749/4885CFTR 386/4885 |
| US-12458635-B2 | Pharmaceutical composition and administrations thereof | CYP3A5, CYP4B1, CYP3A4 | ALDH1A1 629/4885ATM 4854/4885CFTR 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.