Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27323217 | 0.88 | P4HB (0.49) | TSHRSLC6A2SLC6A4SLC6A3P4HB | |
| SCHEMBL30726149 | 0.78 | P4HB (0.47) | TSHRP4HBALDH1A1KDM4EHPGD | |
| SCHEMBL6072641 | 0.78 | AKR1C3 (0.50) | AKR1C3ALDH1A1RAB9AHPGD | |
| SCHEMBL11653388 | 0.78 | TSHR (0.50) | TSHRSRD5A2AKR1C3CYP2C8CYP2C9 | |
| SCHEMBL27657200 | 0.76 | AKR1C3 (0.48) | AKR1C3CYP2C9SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11658107 | 0.75 | GRIN2D (0.48) | TSHRSRD5A2AKR1C3CYP2C8CYP2C9 | |
| SCHEMBL19285676 | 0.75 | GAA (0.49) | AKR1C3CYP2C9SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31676651 | 0.73 | AKR1C3 (0.52) | TSHRAKR1C3CDC25BATMALDH1A1 | |
| SCHEMBL2867843 | 0.72 | AKR1C3 (0.43) | AKR1C3CYP2C8CYP2C9ALDH1A1RAB9A | |
| SCHEMBL11808128 | 0.71 | SLC6A2 (0.66) | TSHRAKR1C3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080275-A | POLYMERIZATION INITIATOR, ETHYLENICALLY UNSATURATED MONOMER | STAUFFER CHEMICAL COMPANY (US) | 1978-03-21 | — | — | US | claimed |