Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11655145 | 0.88 | TSHR (0.49) | P4HBALDH1A1TSHRSLC6A4SLC6A2 | |
| SCHEMBL30726149 | 0.86 | P4HB (0.47) | P4HBALDH1A1TSHRMAPTHTR2A | |
| SCHEMBL2257068 | 0.81 | GABRA1 (0.52) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL5575146 | 0.79 | TSHR (0.40) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL8411705 | 0.76 | P4HB (0.66) | P4HBTSHRHTR2AHTR2CHTR2B | |
| SCHEMBL30726152 | 0.74 | P4HB (0.40) | P4HBHTR2AHTR2CHTR2B | |
| SCHEMBL13020024 | 0.73 | P4HB (0.50) | P4HBHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL15702021 | 0.73 | P4HB (0.50) | P4HBHTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL19834617 | 0.72 | GABRA1 (0.43) | ALDH1A1TSHRTP53GAAMAPT | |
| SCHEMBL2935940 | 0.72 | GABRA1 (0.48) | ALDH1A1TSHRTP53GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1030682-C | Method for preparating N-aryl-3-aryl-4.5-dihydro-IH-pyrazole-l-carboxamides | ROHM AND HASS CORP (US) | 1996-01-17 | — | — | CN | disclosed |
| CN-85101497-A | Process for the preparation of N-aryl-3-aryl-4, 5-dihydro-1H-pyrazole-1-carboxamides | — | 1986-07-16 | — | — | CN | disclosed |