Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27323217 | 0.86 | P4HB (0.49) | P4HBALDH1A1MAPTHPGDTSHR | |
| SCHEMBL30726152 | 0.84 | P4HB (0.40) | P4HBIRAK4HTTHTR2AHTR2C | |
| SCHEMBL1002816 | 0.82 | HTT (0.50) | IRAK4HTTKDM4EALDH1A1MAPT | |
| SCHEMBL3377091 | 0.81 | IRAK4 (0.47) | IRAK4HTTKDM4EALDH1A1MAPT | |
| SCHEMBL8508451 | 0.81 | IRAK4 (0.47) | IRAK4HTTKDM4EALDH1A1MAPT | |
| SCHEMBL17374631 | 0.81 | IRAK4 (0.47) | IRAK4HTTKDM4EALDH1A1MAPT | |
| SCHEMBL8507009 | 0.81 | IRAK4 (0.47) | IRAK4HTTKDM4EALDH1A1MAPT | |
| SCHEMBL21438839 | 0.81 | IRAK4 (0.38) | IRAK4HTTKDM4EALDH1A1MAPT | |
| SCHEMBL11655145 | 0.78 | TSHR (0.49) | P4HBKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL19143527 | 0.78 | KDM4E (0.49) | IRAK4HTTKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425644-A | Opioid receptor modulators | 埃皮欧黛公司 | 2024-01-19 | — | — | CN | disclosed |