Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.39 |
| ▸ | HTR7 | P34969 | 17/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652288 | 0.92 | HTR1A (0.39) | HTR1AHTR7 | |
| SCHEMBL11650638 | 0.89 | HTR1A (0.46) | HTR1AHTR7 | |
| SCHEMBL11649928 | 0.87 | HTR1A (0.39) | HTR1AHTR7 | |
| SCHEMBL11653714 | 0.86 | MAPK1 (0.45) | HTR1AHTR7MAPK1 | |
| SCHEMBL11653595 | 0.86 | MAPK1 (0.45) | HTR1AHTR7MAPK1 | |
| SCHEMBL11650874 | 0.79 | HTR1A (0.46) | HTR1AHTR7 | |
| SCHEMBL11650431 | 0.78 | HTR1A (0.45) | HTR1AHTR7 | |
| SCHEMBL11645738 | 0.76 | HTR1A (0.38) | HTR1AHTR7 | |
| SCHEMBL11652409 | 0.75 | LMNA (0.38) | MAPK1 | |
| SCHEMBL11653199 | 0.72 | ELANE (0.39) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125718-A | Amino-substituted tetracyclic compounds | AKZONA INCORPORATED (US) | 1978-11-14 | — | — | US | claimed |
| US-4125718-A | Amino-substituted tetracyclic compounds | AKZONA INCORPORATED (US) | 1978-11-14 | — | — | US | disclosed |
| US-4062840-A | Amino-substituted 1,2,3,4-tetrahydro-9H-tribenzo[b,d,f]azepines | AKZONA INCORPORATED (US) | 1977-12-13 | — | — | US | disclosed |
| US-3950425-A | Amino-substituted tetracyclic compounds | AKZONA INCORPORATED (US) | 1976-04-13 | — | — | US | disclosed |