Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11655661 | 0.87 | MAOB (0.56) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL656140 | 0.82 | LMNA (0.70) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL656139 | 0.82 | LMNA (0.70) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL30791476 | 0.82 | MAPT (0.56) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL30791484 | 0.82 | MAPT (0.56) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL27969144 | 0.81 | MAOB (0.56) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL21647110 | 0.81 | TYR (0.72) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL21647126 | 0.81 | TYR (0.72) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL29837044 | 0.81 | TYR (0.72) | MAOBMAPTCYP1B1TYRMAPK1 | |
| SCHEMBL21647132 | 0.78 | MAPT (0.68) | MAOBMAPTCYP1B1TYRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759112-B2 | Multifunctional reference system for analyte determinations by fluorescence | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8759112-B2 | Multifunctional reference system for analyte determinations by fluorescence | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20080014655-A1 | Multifunctional Reference System For Analyte Determinations By Fluorescence | ROCHE DIAGNOSTICS OPERATIONS, INC. (IN) | 2008-01-17 | — | — | US | disclosed |
| US-20080014655-A1 | Multifunctional Reference System For Analyte Determinations By Fluorescence | ROCHE DIAGNOSTICS OPERATIONS, INC. (IN) | 2008-01-17 | — | — | US | disclosed |