Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662324 | 0.91 | POLB (0.47) | POLBNPSR1MAPTHTTPIN1 | |
| SCHEMBL5536414 | 0.87 | POLB (0.51) | POLBNPSR1MAPTHTTPIN1 | |
| SCHEMBL11654734 | 0.86 | MAPT (0.49) | POLBNPSR1MAPTHTTTSHR | |
| SCHEMBL11659789 | 0.86 | ALDH1A1 (0.57) | POLBTSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL11662869 | 0.84 | PPARA (0.66) | POLBNPSR1MAPTHTTTSHR | |
| SCHEMBL24497220 | 0.83 | POLB (0.50) | POLBNPSR1MAPTHTTPIN1 | |
| SCHEMBL11661529 | 0.81 | KCNN4 (0.52) | POLBMAPTTSHRCYP1A2CYP3A4 | |
| SCHEMBL11659074 | 0.81 | PPARA (0.61) | POLBMAPTHTTTSHRABCB11 | |
| SCHEMBL27313970 | 0.79 | PIN1 (0.49) | POLBNPSR1MAPTHTTPIN1 | |
| SCHEMBL27538707 | 0.78 | POLB (0.46) | POLBNPSR1MAPTHTTPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4107329-A | Fluorinated compounds as therapeutics | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |