Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228331 | 0.80 | POLB (0.52) | PIN1TSHRPOLBNPSR1LMNA | |
| SCHEMBL2824491 | 0.79 | PPARA (0.71) | PIN1TSHRPPARAABCB11CYP1A2 | |
| SCHEMBL11655878 | 0.79 | POLB (0.51) | PIN1TSHRPPARAABCB11CYP1A2 | |
| SCHEMBL5536414 | 0.79 | POLB (0.51) | PIN1TSHRPPARAABCB11CYP1A2 | |
| SCHEMBL24497220 | 0.78 | POLB (0.50) | PIN1TSHRPPARAABCB11CYP1A2 | |
| SCHEMBL27352386 | 0.78 | TSHR (0.51) | PIN1TSHRPPARAABCB11CYP1A2 | |
| SCHEMBL10654872 | 0.78 | PPARA (0.55) | PIN1TSHRPPARAABCB11CYP1A2 | |
| SCHEMBL11358611 | 0.77 | OPRK1 (0.63) | PIN1TSHRPPARAABCB11CYP1A2 | |
| SCHEMBL28230446 | 0.77 | PIN1 (0.49) | PIN1TSHRPPARAABCB11CYP1A2 | |
| SCHEMBL28082486 | 0.76 | PPARA (0.43) | PIN1TSHRPPARAABCB11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028100-C | Process for preparing phenoxy-heterocyclic compounds | MIDICINE INST CHINESE MEDICAL (CN) | 1995-04-05 | — | — | CN | disclosed |
| CN-1051039-A | Phenoxy group-heterogeneous ring compound | MERRELL DOW PHARMA (US) | 1991-05-01 | — | — | CN | disclosed |