Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NMT1 | P30419 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660127 | 1.00 | TDP1 (0.61) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL11182821 | 0.81 | TDP1 (0.55) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL27562010 | 0.81 | TDP1 (0.55) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL28044354 | 0.79 | TDP1 (0.53) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL455439 | 0.78 | TDP1 (0.70) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL6850999 | 0.78 | KDM4E (0.79) | TDP1POLBNPC1RAB9AKIF11 | |
| SCHEMBL1275920 | 0.78 | ALDH1A1 (0.70) | TDP1POLBNPC1RAB9AKDM4E | |
| SCHEMBL61417 | 0.76 | TDP1 (1.00) | TDP1POLBNPC1RAB9AKDM4E | |
| SCHEMBL11650361 | 0.76 | EPHX2 (0.61) | TGM2MAPTSMN1; SMN2ALDH1A1 | |
| Fluoride SCHEMBL11790965 | 0.76 | TDP1 (0.67) | TDP1POLBNPC1RAB9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104301-A | BLOWING AGENTS | ARMSTRONG CORK COMPANY (US) | 1978-08-01 | — | — | US | disclosed |