Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 12/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664100 | 0.85 | NFKB1 (0.42) | PTGFRPTGER3TBXA2RPTGER1OXER1 | |
| SCHEMBL11658048 | 0.85 | NFKB1 (0.42) | PTGFRPTGER3TBXA2RPTGER1OXER1 | |
| SCHEMBL11657938 | 0.84 | LTA4H (0.35) | PTGFRPTGER3TBXA2RPTGER1LTA4H | |
| SCHEMBL11728896 | 0.78 | PTGFR (0.42) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL11728900 | 0.78 | PTGFR (0.42) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL11654731 | 0.75 | NFKB1 (0.42) | PTGFRPTGER3TBXA2RPTGER1OXER1 | |
| SCHEMBL11660315 | 0.74 | PTGFR (0.41) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL11690272 | 0.72 | PTGFR (0.60) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL11661119 | 0.72 | NFKB1 (0.38) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL11690547 | 0.72 | PTGFR (0.60) | PTGFRPTGER3TBXA2RPTGER1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | claimed |
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |