Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 11/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728900 | 1.00 | PTGFR (0.42) | PTGFRTBXA2RPTGER3PTGER1THRB | |
| SCHEMBL11732048 | 0.89 | LTA4H (0.41) | PTGFRTBXA2RPTGER3PTGER1LTA4H | |
| SCHEMBL11732036 | 0.89 | LTA4H (0.41) | PTGFRTBXA2RPTGER3PTGER1LTA4H | |
| SCHEMBL11728906 | 0.86 | LTA4H (0.39) | PTGFRTBXA2RPTGER3PTGER1LTA4H | |
| SCHEMBL11728916 | 0.86 | LTA4H (0.39) | PTGFRTBXA2RPTGER3PTGER1LTA4H | |
| SCHEMBL11847837 | 0.85 | LTA4H (0.36) | PTGFRTBXA2RPTGER3PTGER1THRB | |
| SCHEMBL11847831 | 0.85 | LTA4H (0.36) | PTGFRTBXA2RPTGER3PTGER1THRB | |
| SCHEMBL11656395 | 0.78 | PTGFR (0.44) | PTGFRTBXA2RPTGER3PTGER1THRB | |
| SCHEMBL11729663 | 0.76 | PTGFR (0.38) | PTGFRTBXA2RPTGER3PTGER1THRB | |
| SCHEMBL11729672 | 0.76 | PTGFR (0.38) | PTGFRTBXA2RPTGER3PTGER1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055596-A | PHARMACEUTICALS | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3991106-A | FOR ESTRUS SYNCHRONIZATION AND TREATMENT OF INFERTILITY | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |