Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | PTPRG | P23470 | 3/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657906 | 0.81 | IDO1 (0.50) | IDO1MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11359685 | 0.76 | EPHX1 (0.51) | SIGMAR1KCNH2L3MBTL1 | |
| SCHEMBL10930316 | 0.76 | IDO1 (0.59) | IDO1PTPRGPTPRCMAPTSMN1; SMN2 | |
| SCHEMBL11661930 | 0.75 | IDO1 (0.50) | IDO1MAPTALDH1A1SMN1; SMN2S1PR5 | |
| SCHEMBL11649453 | 0.74 | IDO1 (0.57) | IDO1PTPRGPTPRCMAPTALDH1A1 | |
| SCHEMBL11664604 | 0.73 | SMN1; SMN2 (0.53) | IDO1ALDH1A1SMN1; SMN2SIGMAR1TAAR1 | |
| SCHEMBL11657752 | 0.73 | IDO1 (0.56) | IDO1MAPTALDH1A1KMT2A | |
| SCHEMBL11444326 | 0.72 | IDO1 (0.62) | IDO1PTPRGPTPRCMAPTPNMT | |
| SCHEMBL11655628 | 0.71 | TERT (0.41) | MAPTSMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL30791545 | 0.71 | EPHX2 (0.61) | KDM4EALDH1A1SMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4112116-A | Certain cyclopropane thiolcarboxylates and use thereof as miticides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-05 | — | — | US | disclosed |