Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230414 | 0.83 | KDM4E (0.50) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL163147 | 0.70 | GAA (0.38) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1165495 | 0.70 | LMNA (0.35) | GAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL2893384 | 0.69 | POLB (0.58) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1165522 | 0.69 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL1165311 | 0.69 | ALDH1A1 (0.33) | MAPTALDH1A1 | |
| SCHEMBL6243610 | 0.68 | GAA (0.59) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1165093 | 0.68 | NPC1 (0.33) | ALDH1A1POLB | |
| SCHEMBL9279836 | 0.68 | GAA (0.63) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL18919554 | 0.67 | GAA (0.69) | KDM4EGAAMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039894-A1 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | claimed |
| EP-2107058-A1 | Substituted enaminothiocarbonyl compounds | Bayer CropScience AG (DE) | 2009-10-07 | — | — | EP | claimed |
| EP-2262798-B1 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | BAYER IP GMBH (DE) | 2016-06-08 | — | — | EP | disclosed |
| EP-2262798-B1 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | BAYER IP GMBH (DE) | 2016-06-08 | — | — | EP | disclosed |
| US-8563584-B2 | Substituted enaminothiocarbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| US-8563584-B2 | Substituted enaminothiocarbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| US-8563584-B2 | Substituted enaminothiocarbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| US-20110039894-A1 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110039894-A1 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110039894-A1 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| EP-2262798-A2 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009121507-A2 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009121507-A2 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-10-08 | — | — | WO | disclosed |
| EP-2107058-A1 | Substituted enaminothiocarbonyl compounds | Bayer CropScience AG (DE) | 2009-10-07 | — | — | EP | disclosed |
| EP-2107058-A1 | Substituted enaminothiocarbonyl compounds | Bayer CropScience AG (DE) | 2009-10-07 | — | — | EP | disclosed |
| EP-2107058-A1 | Substituted enaminothiocarbonyl compounds | Bayer CropScience AG (DE) | 2009-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039894-A1 | SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS | DDT, PTMS, AADAC | KDM4E 1959/4885GAA 1688/4885MAPT 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.