SCHEMBL2893384

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12869192	0.82	POLB (0.83)	POLBALDH1A1GAAMAPTSMN1; SMN2
	SCHEMBL230414	0.75	KDM4E (0.50)	POLBALDH1A1KDM4EGAAMAPT
	SCHEMBL9999989	0.75	POLB (0.71)	POLBALDH1A1GAAL3MBTL1SMN1; SMN2
	SCHEMBL9544841	0.74	POLB (1.00)	POLBALDH1A1KDM4EGAAMAPT
	SCHEMBL2892730	0.70	MT-CO2 (0.39)	ALDH1A1L3MBTL1MT-CO2MEN1KMT2A
	SCHEMBL1165738	0.69	KDM4E (0.50)	POLBALDH1A1KDM4EGAAMAPT
	SCHEMBL2890160	0.69	MT-CO2 (0.37)	ALDH1A1MAPTMT-CO2MEN1KMT2A
	SCHEMBL6243610	0.68	GAA (0.59)	ALDH1A1KDM4EGAAMAPTL3MBTL1
	SCHEMBL12869177	0.68	POLB (0.61)	POLBALDH1A1KDM4EGAAMAPT
	SCHEMBL9279836	0.68	GAA (0.63)	ALDH1A1KDM4EGAAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.