Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | NPC1 | O15118 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chrysin Dimethyl Ether SCHEMBL29403280 | 0.86 | ABCG2 (1.00) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| Chrysin Dimethyl Ether SCHEMBL1676012 | 0.86 | ABCG2 (1.00) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| SCHEMBL11656201 | 0.85 | AR (0.65) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| SCHEMBL17193761 | 0.81 | ABCB1 (0.73) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| SCHEMBL17193741 | 0.81 | MAOB (0.81) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| SCHEMBL31238392 | 0.81 | KDM4E (0.83) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| SCHEMBL29979584 | 0.81 | L3MBTL1 (0.79) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| SCHEMBL17185524 | 0.80 | ABCB1 (0.75) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| SCHEMBL17185533 | 0.80 | ABCB1 (0.75) | KDM4EABCG2ALDH1A1NPC1MEN1 | |
| SCHEMBL17185542 | 0.80 | ABCB1 (0.75) | KDM4EABCG2ALDH1A1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105781-A | ANTIALLERGENS FOR TREATMENT OF ASTHMA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-08-08 | — | — | US | disclosed |
| US-4049664-A | ANTIALLERGENS, ANTIASTHMATICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-09-20 | — | — | US | disclosed |
| US-3965122-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-06-22 | — | — | US | disclosed |