Chrysin Dimethyl Ether

Chrysin Dimethyl Ether

SCHEMBL29403280

COc1cc(OC)c2c(=O)cc(-c3ccccc3)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCG2 Q9UNQ0 5/20 1.00
▸ ALDH1A1 P00352 5/20 1.00
▸ KDM4E B2RXH2 4/20 1.00
▸ MEN1 O00255 3/20 1.00
▸ KMT2A Q03164 3/20 1.00
▸ NPC1 O15118 2/20 1.00
▸ RAB9A P51151 1/20 1.00
▸ ABCB1 P08183 6/20 0.82
▸ CYP3A4 P08684 4/20 0.75
▸ MAPT P10636 3/20 0.75
▸ TP53 P04637 2/20 0.75
▸ SMN1; SMN2 Q16637 1/20 0.75
▸ HPGD P15428 2/20 0.74
▸ HSD17B10 Q99714 2/20 0.74
▸ AR P10275 2/20 0.74
▸ CYP2C9 P11712 2/20 0.73
▸ CYP2C19 P33261 2/20 0.73
▸ TSHR P16473 1/20 0.73
▸ PPARG P37231 1/20 0.73
▸ CCNC P24863 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chrysin Dimethyl Ether SCHEMBL1676012 1.00 ABCG2 (1.00) ABCG2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL31238392 0.91 KDM4E (0.83) ABCG2ALDH1A1KDM4EMEN1KMT2A
Trimethylapigenin SCHEMBL29350875 0.90 ABCB1 (1.00) ABCG2ALDH1A1KDM4EMEN1KMT2A
Trimethylapigenin SCHEMBL1421585 0.90 ABCB1 (1.00) ABCG2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL20100898 0.87 KDM4E (0.78) ABCG2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL4051739 0.87 KDM4E (0.78) ABCG2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL4165061 0.87 ABCB1 (0.81) ABCG2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL19235588 0.86 ALDH1A1 (0.76) ABCG2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL17193739 0.86 ABCB1 (0.87) ABCG2ALDH1A1KDM4EMEN1KMT2A
SCHEMBL13945269 0.86 ABCB1 (0.78) ABCG2ALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500283-B1 A FORMULATION FOR IMPROVING PHYSICAL ENDURANCE IN ATHLETES AND A METHOD FOR PREPARING THE SAME AUREA BIOLABS PRIVATE LTD (IN) 2026-02-18 — — EP claimed
CN-111971042-B Granulin for identifying as causative agent of Alzheimer's disease, composition and method for inhibiting aggregation of granulin and treating Alzheimer's disease 刘承铉 2024-01-02 — — CN claimed
CN-122029153-A Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof 德明药泰生物技术(深圳)有限公司 2026-05-12 — — CN disclosed
CN-121816180-A Preparation of penis erection gel and its preparing process MD产品&服务有限公司 2026-04-07 — — CN disclosed
US-12590094-B2 Compounds for the treatment of neurodegenerative and metabolic disorders UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-03-31 — — US disclosed
CN-121577766-A Method, system and application for detecting adulteration in vegetable oil 长沙市食品药品检验所 2026-02-27 — — CN disclosed
EP-3500283-B1 A FORMULATION FOR IMPROVING PHYSICAL ENDURANCE IN ATHLETES AND A METHOD FOR PREPARING THE SAME AUREA BIOLABS PRIVATE LTD (IN) 2026-02-18 — — EP disclosed
CN-119968127-A Animal food compositions with improved palatability and customizable properties and methods of making the same 玛氏公司 2025-05-09 — — CN disclosed
CN-118995656-A Demethylation functional enzyme of flavonoid compound, and encoding gene and application thereof 上海中医药大学 2024-11-22 — — CN disclosed
CN-116035988-B Anti-dandruff and anti-drop ginger-like composition, and preparation method and application thereof 泉后(广州)生物科技研究院有限公司 2024-09-24 — — CN disclosed
CN-118415234-A Myotonin oxidation-resistant nano film based on Maillard reaction and preparation method and application thereof 沈阳农业大学 2024-08-02 — — CN disclosed
CN-114867486-B Composition containing black ginger extract and composition for oral administration 丸善制药株式会社 2023-05-30 — — CN disclosed
CN-116114778-A Food composition for promoting testosterone level and preparation method thereof 广州正广生物科技有限公司 2023-05-16 — — CN disclosed
CN-116035988-A Anti-dandruff and anti-drop ginger-like composition, and preparation method and application thereof 泉后(广州)生物科技研究院有限公司 2023-05-02 — — CN disclosed
US-20230041523-A1 COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE AND METABOLIC DISORDERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2023-02-09 — — US disclosed
CN-113694155-B Kaempferia galanga total flavone extract and preparation method and application thereof 清华大学 2022-10-18 — — CN disclosed
CN-114867486-A Composition containing Heijiang extract and oral composition 丸善制药株式会社 2022-08-05 — — CN disclosed
US-20220105072-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES COMPLICATIONS COMPRISING NOVEL CHRYSIN DERIVATIVE COMPOUND AS ACTIVE INGREDIENT FRONTBIO INC (KR) 2022-04-07 — — US disclosed
CN-114173797-A Product infused with cannabis with enhanced cannabinoid profile user experience 埃克索运营公司 2022-03-11 — — CN disclosed
CN-114098065-A Biological product for improving male functions and preparation method and application thereof 张学记 2022-03-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220105072-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES COMPLICATIONS COMPRISING NOVEL CHRYSIN DERIVATIVE COMPOUND AS ACTIVE INGREDIENT AGER, IAPP, GCG ABCG2 1849/4885ALDH1A1 3899/4885KDM4E 3203/4885
US-12590094-B2 Compounds for the treatment of neurodegenerative and metabolic disorders TXN2, SMN1; SMN2, SNCA ABCG2 1792/4885ALDH1A1 237/4885KDM4E 4079/4885
US-20230041523-A1 COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE AND METABOLIC DISORDERS NLN, GLS, PRNP ABCG2 2717/4885ALDH1A1 495/4885KDM4E 2500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback